PLK5 Antibody

Code CSB-PA003821
Size US$100
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  • Western Blot analysis of COLO205 cells using PLK-5 Polyclonal Antibody
  • Western Blot analysis of Jurkat K562 NIH-3T3 cells using PLK-5 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
PLK5
Alternative Names
PLK5 antibody; PLK5P antibody; FG060302 antibody; Inactive serine/threonine-protein kinase PLK5 antibody; Polo-like kinase 5 antibody; PLK-5 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human PLK-5.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:10000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Inactive serine/threonine-protein kinase that plays a role in cell cycle progression and neuronal differentiation.
Gene References into Functions
  1. we report a three-nucleotide deletion near the C-region of Plk5 that is specifically associated with the lymphatic metastasis in patients with clear cell renal cell carcinoma PMID: 26908440
  2. The human polo-like kinase 5 gene is significantly silenced in astrocytoma and glioblastoma multiforme by promoter hypermethylation, suggesting a tumor suppressor function for this gene. PMID: 21245385
Subcellular Location
Nucleus, nucleolus. Cytoplasm.
Protein Families
Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily
Tissue Specificity
Expressed in the brain, neurons and glial cells. Also expressed in highly differentiated cells, such as the serous acini in the parotid gland, distal and proximal tubules of the kidney, tubules of the seminal gland, Kupffer cells and some hepatocytes in t
Database Links

HGNC: 27001

KEGG: hsa:126520

STRING: 9606.ENSP00000466248

UniGene: Hs.195352

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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