RPS7 Antibody

Datasheet

Code	CSB-PA020476LA01HU
Size	US$166
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Image	IHC image of CSB-PA020476LA01HU diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. IHC image of CSB-PA020476LA01HU diluted at 1:100 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated ABC system.
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) RPS7 Polyclonal antibody

Uniprot No.

P62081

Target Names

RPS7

Alternative Names

40S ribosomal protein S7 antibody; DBA8 antibody; Ribosomal protein S7 antibody; RPS 7 antibody; rps7 antibody; RS7_HUMAN antibody; S7 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human 40S ribosomal protein S7 protein (1-194AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The RPS7 Antibody (Product code: CSB-PA020476LA01HU) is Non-conjugated. For RPS7 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA020476LB01HU	RPS7 Antibody, HRP conjugated	ELISA
FITC	CSB-PA020476LC01HU	RPS7 Antibody, FITC conjugated
Biotin	CSB-PA020476LD01HU	RPS7 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Required for rRNA maturation.

Gene References into Functions

BCCIPbeta interacts with the central basic region in S7 protein and regulates the extraribosomal distribution of S7. PMID: 28510697
RPS7 role in cell proliferation in the context of Hepatitis B virus-related hepatocellular carcinoma.SIRT7 trans-represses RPS7 gene in the presence of HBx protein. PMID: 26442981
Low expression of RPS7 is associated with colorectal cancer. PMID: 26735579
Knockdown of RPS7 resulted in increased expression of P85alpha, P110alpha, and AKT2. PMID: 24244431
The study found two ribosomal proteins, RPS7 and RPL13A that interact with the HMG (high-mobility group) box domain of SRY. PMID: 21114473
S7 binds to MDM2, in vitro and in vivo, and the interaction between MDM2 and S7 leads to modulation of MDM2-p53 binding by forming a ternary complex among MDM2, p53 and S7. PMID: 17310983

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Involvement in disease

Diamond-Blackfan anemia 8 (DBA8)

Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

Protein Families

Eukaryotic ribosomal protein eS7 family

Database Links

HGNC: 10440

OMIM: 603658

KEGG: hsa:6201

STRING: 9606.ENSP00000339095

UniGene: Hs.534346

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Service

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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