SCARF2 Antibody

Code CSB-PA042899
Size US$297
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  • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using SCARF2 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SCARF2 Polyclonal antibody
Uniprot No.
Target Names
SCARF2
Alternative Names
SCARF2 antibody; SREC2 antibody; SREPCR antibody; Scavenger receptor class F member 2 antibody; SRECRP-1 antibody; Scavenger receptor expressed by endothelial cells 2 protein antibody; SREC-II antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from internal of Human SCARF2.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:50-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Probable adhesion protein, which mediates homophilic and heterophilic interactions. In contrast to SCARF1, it poorly mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL).
Gene References into Functions
  1. the full VDEGS phenotype may include sclerocornea resulting from homozygosity or compound heterozygosity for loss of function variants in SCARF2. PMID: 24478002
  2. Mutations in SCARF2 are responsible for Van Den Ende-Gupta syndrome. PMID: 20887961
  3. SRECII binds to SRECI and has a similar tissue distribution pattern PMID: 12154095
Involvement in disease
Van den Ende-Gupta syndrome (VDEGS)
Subcellular Location
Membrane; Single-pass type I membrane protein.
Tissue Specificity
Predominantly expressed in endothelial cells. Expressed in heart, placenta, lung, kidney, spleen, small intestine and ovary.
Database Links

HGNC: 19869

OMIM: 600920

KEGG: hsa:91179

STRING: 9606.ENSP00000266214

UniGene: Hs.474251

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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