SERPINA9 Antibody

Code CSB-PA895479
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA895479(SERPINA9 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA895479(SERPINA9 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: 293T cells, 231 cells, U937 cells, Raji cells, Primary antibody: CSB-PA895479(SERPINA9 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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Product Details

Uniprot No.
Target Names
SERPINA9
Alternative Names
Centerin antibody; GCET1 antibody; Germinal center B cell expressed transcript 1 antibody; Germinal center B-cell-expressed transcript 1 protein antibody; Seprin A9 antibody; Serine proteinase inhibitor A11 antibody; Serpin A9 antibody; Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 9 antibody; Serpin peptidase inhibitor clade A member 9 antibody; SERPINA11 antibody; SERPINA11b antibody; Serpina9 antibody; SPA9_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide of Human SERPINA9
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
WB 1:500-1:2000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Protease inhibitor that inhibits trypsin and trypsin-like serine proteases (in vitro). Inhibits plasmin and thrombin with lower efficiency (in vitro).
Gene References into Functions
  1. Diagnostic Utility of the Germinal Center-associated Markers GCET1, HGAL, and LMO2 in Hematolymphoid Neoplasms. PMID: 25203428
  2. Results report the cloning of germinal center B-cell expressed transcripts 1 and 2 (GCET1 and 2), and show that both are expressed in follicular lymphoma and diffuse large B-cell lymphoma with germinal center B-cell differentiation. PMID: 12819018
  3. The cloning, expression and molecular characterization of recombinant serpina9 (centerin) are reported. PMID: 17447896
  4. Gcet-1 protein expression is restricted to a subset of germinal center B cells, establishing the existence of a distinct heterogeneity among normal and neoplastic germinal center B cells PMID: 17898315
  5. Immunohistochemical expression of centerin further defines the germinal center cell origin of a subgroup of lymphomas. PMID: 18550480
  6. serpinA9 was associated with stroke in both whites and blacks PMID: 18799872
  7. Observational study of gene-disease association. (HuGE Navigator) PMID: 19023099
  8. Observational study of gene-disease association. (HuGE Navigator) PMID: 17975119

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Subcellular Location
[Isoform 1]: Secreted.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm.; [Isoform 4]: Cytoplasm.; [Isoform 5]: Cytoplasm.; [Isoform 6]: Cytoplasm.; [Isoform 7]: Membrane; Single-pass type II membrane protein.
Protein Families
Serpin family
Tissue Specificity
Highly expressed in normal germinal center (GC) B-cells and GC B-cell-derived malignancies.
Database Links

HGNC: 15995

OMIM: 615677

KEGG: hsa:327657

STRING: 9606.ENSP00000337133

UniGene: Hs.317970

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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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