SLC25A32 Antibody

Code CSB-PA872477LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: Mouse kidney tissue, Mouse skeletal muscle tissue
    All lanes: SLC25A32 antibody at 3µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 36 kDa
    Observed band size: 36 kDa

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SLC25A32 Polyclonal antibody
Uniprot No.
Target Names
SLC25A32
Alternative Names
SLC25A32; MFT; MFTC; Mitochondrial folate transporter/carrier; Solute carrier family 25 member 32
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Mitochondrial folate transporter/carrier protein (44-88AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The SLC25A32 Antibody (Product code: CSB-PA872477LA01HU) is Non-conjugated. For SLC25A32 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA872477LB01HU SLC25A32 Antibody, HRP conjugated ELISA
FITC CSB-PA872477LC01HU SLC25A32 Antibody, FITC conjugated
Biotin CSB-PA872477LD01HU SLC25A32 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Transports folate across the inner membranes of mitochondria. Can also transport FAD across the mitochondrial inner membrane.
Gene References into Functions
  1. These data demonstrate that the loss of functional Slc25a32 results in cranial neural tube defects (NTDs) in mice and has also been observed in a human NTD patient. PMID: 29666258
  2. A novel SLC25A32 homozygous variant is associated with severe neuromuscular phenotype. PMID: 28443623
  3. SLC25A32 gene polymorphism could be a risk factor for lower folate concentration and future fracture. PMID: 24354357
  4. identified residues in the walls and at the base of the transport cavity that are involved in substrate recognition by the MFT PMID: 21768094
  5. Patient with SLC25A32 deficiency was able to have a successful pregnancy after fertilization in vitro. PMID: 19362304

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Involvement in disease
Exercise intolerance, riboflavin-responsive (RREI)
Subcellular Location
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein Families
Mitochondrial carrier (TC 2.A.29) family
Tissue Specificity
Ubiquitous.
Database Links

HGNC: 29683

OMIM: 610815

KEGG: hsa:81034

STRING: 9606.ENSP00000297578

UniGene: Hs.532265

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