SLC2A12 Antibody

Datasheet

Code	CSB-PA067005
Size	US$166
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Image	The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA067005 at dilution 1/30. (Original magnification: ×200)
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q8TD20

Target Names

SLC2A12

Alternative Names

Glucose transporter type 12 antibody; GLUT 12 antibody; GLUT-12 antibody; GLUT12 antibody; GLUT8 antibody; GTR12_HUMAN antibody; SLC2A12 antibody; Solute carrier family 2 (facilitated glucose transporter) member 12 antibody; Solute carrier family 2 facilitated glucose transporter member 12 antibody; Solute carrier family 2 member 12 antibody; Solute carrier family 2, facilitated glucose transporter member 12 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide of Human SLC2A12

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:1000-1:2000
IHC	1:50-1:100

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Insulin-independent facilitative glucose transporter.

Gene References into Functions

GLUT12-knockdown completely abrogated high glucose-induced migration, indicating that GLUT12 functionally participates in sensing high glucose concentrations. PMID: 29187448
GLUT12 is a versatile transporter: it transports a wide diversity of hexoses, it can work as a Na+ or H+/glucose symporter, and it shows electrogenic properties. PMID: 25855082
findings show the level of expression of GLUT12 was significantly higher in Alzheimer's disease compare to aged controls PMID: 24820014
Intestinal dehydroascorbic acid (DHA) transport is mediated by the facilitative sugar transporters, GLUT2 and GLUT8 PMID: 23396969
Embedded in microvillous (maternal-facing) and basal (fetal-facing) membranes of syncytiotrophoblast, main placental barrier layer. (review) PMID: 12583599
Glucose transport properties and hexose affinities of GLUT12. PMID: 12914765
GLUT12 protein was localized to the apical membrane of human and rat distal tubules and collecting ducts. Levels of both GLUT1 and GLUT12 are elevated in animal models of hypertension and diabetic nephropathy. PMID: 16091581
GLUT4 and GLUT12 were predominantly expressed in type I oxidative fibers; however, GLUT5 was expressed predominantly in type II (white) fibers PMID: 16803853
Translocation of GLUT12 in cultured myoblasts was dependent on activation of PI3-K. PMID: 19549745

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Subcellular Location

Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein. Cytoplasm, perinuclear region.

Protein Families

Major facilitator superfamily, Sugar transporter (TC 2.A.1.1) family, Glucose transporter subfamily

Tissue Specificity

Predominantly expressed in skeletal muscle, heart and prostate, with lower levels in brain, placenta and kidney.

Database Links

HGNC: 18067

OMIM: 610372

KEGG: hsa:154091

STRING: 9606.ENSP00000275230

UniGene: Hs.486508

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Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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