SLC30A7 Antibody

Code CSB-PA836732LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: Mouse heart tissue, Mouse skeletal muscle tissue
    All lanes: SLC30A7 antibody at 3μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 42 kDa
    Observed band size: 42 kDa

  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA836732LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SLC30A7 Polyclonal antibody
Uniprot No.
Target Names
SLC30A7
Alternative Names
SLC30A7; ZNT7; ZNTL2; Zinc transporter 7; ZnT-7; Solute carrier family 30 member 7; Znt-like transporter 2
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Zinc transporter 7 protein (162-236AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The SLC30A7 Antibody (Product code: CSB-PA836732LA01HU) is Non-conjugated. For SLC30A7 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA836732LB01HU SLC30A7 Antibody, HRP conjugated ELISA
FITC CSB-PA836732LC01HU SLC30A7 Antibody, FITC conjugated
Biotin CSB-PA836732LD01HU SLC30A7 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP.
Gene References into Functions
  1. We observed Bonferroni-corrected statistically significant interactions between albuminuria, urine cadmium levels and polymorphisms in gene SLC30A7 and RAC1. PMID: 28558300
  2. Overexpression of ZnT7 is accompanied by activation of PI3K/Akt pathway and inhibiting HG-induced apoptosis. PMID: 23275032
  3. Intracellular transporters such as ZnT7, influence the transcellular movement of zinc across the enterocyte PMID: 21462106
  4. hZnT-7 is up-regulated in response to cellular zinc depletion in Raji & THP-1 cells. PMID: 17971500
  5. Data show that ZNT7 is extensively present in the Abeta-positive plaques in the cortex of human AD brains. PMID: 18639746

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Subcellular Location
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein.
Protein Families
Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family, SLC30A subfamily
Database Links

HGNC: 19306

OMIM: 611149

KEGG: hsa:148867

STRING: 9606.ENSP00000350278

UniGene: Hs.533903

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