SLC7A3 Antibody

Code CSB-PA855505LA01HU
Size US$166
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  • Immunofluorescent analysis of MCF-7 cells using CSB-PA855505LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SLC7A3 Polyclonal antibody
Uniprot No.
Target Names
SLC7A3
Alternative Names
SLC7A3 antibody; ATRC3 antibody; CAT3 antibody; Cationic amino acid transporter 3 antibody; CAT-3 antibody; CAT3 antibody; Cationic amino acid transporter y+ antibody; Solute carrier family 7 member 3 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Cationic amino acid transporter 3 protein (428-475AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The SLC7A3 Antibody (Product code: CSB-PA855505LA01HU) is Non-conjugated. For SLC7A3 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA855505LB01HU SLC7A3 Antibody, HRP conjugated ELISA
FITC CSB-PA855505LC01HU SLC7A3 Antibody, FITC conjugated
Biotin CSB-PA855505LD01HU SLC7A3 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IF
Recommended Dilution
Application Recommended Dilution
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Mediates the uptake of the cationic amino acids arginine, lysine and ornithine in a sodium-independent manner.
Gene References into Functions
  1. rare hypomorphic variants of SLC7A3 exist in male individuals, SLC7A3 variants possibly contribute to the etiology of autism spectrum disorders in male subjects in association with other genetic factors PMID: 26215737
  2. knockdown impaired AMPK-PPAR-alpha signaling and resulted in lipid accumulation under glucose starvation in liver cells PMID: 25130427
  3. CAT1, CAT2, and CAT3 localized in adult brains but with uneven distribution. PMID: 22870827
  4. is concluded that hCAT-3 is a passive transport system that conducts monovalent cations including L-Arg. PMID: 15737334
  5. It is concluded that similar to hCAT-1, hCAT-3 activity is decreased by PKC via reduction of transporter molecules in the plasma membrane. PMID: 16332251

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Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
Amino acid-polyamine-organocation (APC) superfamily, Cationic amino acid transporter (CAT) (TC 2.A.3.3) family
Tissue Specificity
Highly expressed in thymus, uterus and testis. Detected at lower levels in brain, mammary gland, prostate, salivary gland and fetal spleen. In brain, highest expression in thalamus, hippocampus and amygdala.
Database Links

HGNC: 11061

OMIM: 300443

KEGG: hsa:84889

STRING: 9606.ENSP00000298085

UniGene: Hs.175220

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