SPACA3 Antibody

Datasheet

Code	CSB-PA022454GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q8IXA5

Target Names

SPACA3

Alternative Names

SPACA3 antibody; LYC3 antibody; LYZL3 antibody; SLLP1 antibody; SPRASA antibody; UNQ424/PRO862Sperm acrosome membrane-associated protein 3 antibody; Cancer/testis antigen 54 antibody; CT54 antibody; Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17 antibody; Lysozyme-like protein 3 antibody; Sperm lysozyme-like protein 1 antibody; Sperm protein reactive with antisperm antibodies antibody; Sperm protein reactive with ASA) [Cleaved into: Sperm acrosome membrane-associated protein 3 antibody; membrane form; Sperm acrosome membrane-associated protein 3 antibody; processed form] antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human SPACA3

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.

Gene References into Functions

The levels of antibodies reactive with SPRASA were elevated in infertile women. PMID: 25038051
SLLP1 represents a promising target for the immunotherapy of multiple myeloma. PMID: 26088750
Authors present evidence that the variants could affect the expression levels or function of SPRASA, thereby affecting a couple's fertility. PMID: 24872021
SLLP1 could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane PMID: 12606493
SLLP1 is capable of eliciting B-cell immune responses in vivo in cancer-bearing individuals. PMID: 15475442

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Subcellular Location

[Isoform 1]: Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Single-pass type II membrane protein.; [Isoform 2]: Secreted.

Protein Families

Glycosyl hydrolase 22 family

Tissue Specificity

The processed form is expressed in sperm (at protein level). Expressed in testis, epididymis and placenta.

Database Links

HGNC: 16260

OMIM: 612749

KEGG: hsa:124912

STRING: 9606.ENSP00000269053

UniGene: Hs.434112

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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