STRN Antibody

1. striatin-associated Salt Sensitive Blood Pressure is associated with normal plasma renin activity and reduced epinephrine levels PMID: 28985281
2. The prevalence of STRN-ALK kinase fusions were determined in papillary thyroid cancer of an adult population PMID: 29046324
3. In this review, we summarize the current understanding of the assembly and functions of STRIPAK complexes( striatin-centered multicomponent supramolecular structures containing both kinases and phosphatases), with a special focus on cell signaling and cancer PMID: 26876214
4. we report 2 cases of renal cell carcinomas harboring a novel STRN-ALK fusion PMID: 26848800
5. the "multimodulator" scaffold roles of striatins in the initiation and regulation of the formation of various complex particles and structures, are discussed. PMID: 25501894
6. PP2A/striatin complex modulates microtubule dynamics by regulating MAP2 phosphorylation PMID: 25497017
7. the rapid, nongenomic mineralocorticoid receptor pathway (mediated via striatin) has a role in modulating the interaction between salt intake and blood pressure. PMID: 25368024
8. A recurrent STRN/ALK fusion found in thyroid carcinomas. PMID: 24475247
9. Our data demonstrate that STRN-ALK fusion occurs in a subset of patients with highly aggressive types of thyroid cancer and provide initial evidence suggesting that it may represent a therapeutic target for these patients. PMID: 24613930
10. Striatin orchestrates the regulation of Mst3 by PP2A. PMID: 21985334
11. identify striatin as a molecular scaffold required for rapid, nongenomic estrogen-mediated activation of downstream signaling pathways PMID: 15569929
12. Taken together, splicing variation of SG2NA might have some critical roles in differentiation and maturation in metazoan cells. PMID: 18571342
13. Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia. PMID: 19165527

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HGNC: 11424

OMIM: 614765

KEGG: hsa:6801

STRING: 9606.ENSP00000263918

UniGene: Hs.127486