TAF5L Antibody

Datasheet

Code	CSB-PA004226
Size	US$119
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Image	Western Blot analysis of COS7 cells using TAF5L Polyclonal Antibody
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

O75529

Target Names

TAF5L

Alternative Names

1110005N04Rik antibody; AI849020 antibody; OTTHUMP00000037470 antibody; OTTHUMP00000037471 antibody; PAF65 beta antibody; PAF65-beta antibody; PAF65B antibody; PCAF associated factor 65 beta antibody; PCAF-associated factor 65 beta antibody; TAF 5L antibody; TAF5 like RNA polymerase II p300/CBP associated factor (PCAF) associated factor 65 kD antibody; TAF5 like RNA polymerase II p300/CBP associated factor (PCAF) associated factor 65 kDa antibody; TAF5 like RNA polymerase II p300/CBP associated factor (PCAF) associated factor antibody; TAF5 like RNA polymerase II p300/CBP associated factor associated factor 65 kDa subunit 5L antibody; TAF5 like RNA polymerase II p300/CBP associated factor associated factor 65kDa antibody; TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L antibody; Taf5l antibody; Taf5l protein antibody; TAF5L_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human,Monkey

Immunogen

Synthesized peptide derived from the Internal region of Human TAF5L.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, IHC, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:100-1:300
ELISA	1:10000

Protocols

Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. With TAF6L, acts as an epigenetic regulator essential for somatic reprogramming. Regulates target genes through H3K9ac deposition and MYC recruitment which trigger MYC regulatory network to orchestrate gene expression programs to control embryonic stem cell state.

Gene References into Functions

p300 can acetylate DNA-bound Myc:Max complexes and that acetylated Myc:Max heterodimers efficiently interact with Miz-1 PMID: 16126174
The TAF5L gene on chromosome 1q42 is associated tie type 1 diabetes in Russian patients. PMID: 16206511
p300 or PCAF maintains myoblast viability as effectively as added growth factors through mechanisms requiring the acetyltransferase activity of PCAF but not of p300. PMID: 16672693
latent cytoplasmic coactivator TORC2 mediates target gene activation in response to cAMP signaling by associating with CBP/p300 and increasing its recruitment to a subset of CREB target genes PMID: 17476304
PCAF is a histone acetyltransferase which regulates gene transcription. PCAF interacts physically and functionally with PTEN. PTEN acetylation by PCAF block the ability of PTEN to downregulate PI3-K signalling and to induce G1 cell cycle arrest. PMID: 16829519

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Subcellular Location

Nucleus.

Protein Families

WD repeat TAF5 family

Database Links

HGNC: 17304

KEGG: hsa:27097

STRING: 9606.ENSP00000258281

UniGene: Hs.270621

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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