TAF5L Antibody

Code CSB-PA023093GA01HU
Size US$685
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Product Details

Uniprot No. O75529
Target Names TAF5L
Alternative Names 1110005N04Rik antibody; AI849020 antibody; OTTHUMP00000037470 antibody; OTTHUMP00000037471 antibody; PAF65 beta antibody; PAF65-beta antibody; PAF65B antibody; PCAF associated factor 65 beta antibody; PCAF-associated factor 65 beta antibody; TAF 5L antibody; TAF5 like RNA polymerase II p300/CBP associated factor (PCAF) associated factor 65 kD antibody; TAF5 like RNA polymerase II p300/CBP associated factor (PCAF) associated factor 65 kDa antibody; TAF5 like RNA polymerase II p300/CBP associated factor (PCAF) associated factor antibody; TAF5 like RNA polymerase II p300/CBP associated factor associated factor 65 kDa subunit 5L antibody; TAF5 like RNA polymerase II p300/CBP associated factor associated factor 65kDa antibody; TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L antibody; Taf5l antibody; Taf5l protein antibody; TAF5L_HUMAN antibody
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Immunogen Human TAF5L
Immunogen Species Homo sapiens (Human)
Isotype IgG
Purification Method Antigen Affinity purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications ELISA,WB
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Data

Function Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex.
Gene References into Functions
  1. p300 can acetylate DNA-bound Myc:Max complexes and that acetylated Myc:Max heterodimers efficiently interact with Miz-1 PMID: 16126174
  2. The TAF5L gene on chromosome 1q42 is associated tie type 1 diabetes in Russian patients. PMID: 16206511
  3. p300 or PCAF maintains myoblast viability as effectively as added growth factors through mechanisms requiring the acetyltransferase activity of PCAF but not of p300. PMID: 16672693
  4. latent cytoplasmic coactivator TORC2 mediates target gene activation in response to cAMP signaling by associating with CBP/p300 and increasing its recruitment to a subset of CREB target genes PMID: 17476304
  5. PCAF is a histone acetyltransferase which regulates gene transcription. PCAF interacts physically and functionally with PTEN. PTEN acetylation by PCAF block the ability of PTEN to downregulate PI3-K signalling and to induce G1 cell cycle arrest. PMID: 16829519

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Subcellular Location Nucleus
Protein Families WD repeat TAF5 family
Database Links

HGNC: 17304

KEGG: hsa:27097

STRING: 9606.ENSP00000258281

UniGene: Hs.270621

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