TFPT Antibody

Code CSB-PA023439GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
TFPT
Alternative Names
Amida antibody; INO80 complex subunit F antibody; INO80F antibody; Protein FB1 antibody; TCF3 (E2A) fusion partner (in childhood Leukemia) antibody; TCF3 fusion partner antibody; TFPT antibody; TFPT_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human TFPT
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Appears to promote apoptosis in a p53/TP53-independent manner.; Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
Gene References into Functions
  1. TCF3/E2A is Conserved Specific Coregulators of the p21:PUMA Expression Ratio. PMID: 23684607
  2. Although p53 is a main regulator of apoptosis in mammalian cells, the Tfpt induced apoptosis appears p53-independent. PMID: 17041757
  3. FB1 is an important binding partner and a functional regulator of U19/EAF2, EAF1, and/or ELL. PMID: 17395368
Involvement in disease
A chromosomal aberration involving TFPT is a cause of pre-B-cell acute lymphoblastic leukemia (B-ALL). Inversion inv(19)(p13;q13) with TCF3.
Subcellular Location
Nucleus.
Database Links

HGNC: 13630

OMIM: 609519

KEGG: hsa:29844

STRING: 9606.ENSP00000375639

UniGene: Hs.590939

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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