TRIM45 Antibody

Datasheet

Code	CSB-PA572337
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA572337(TRIM45 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA572337(TRIM45 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q9H8W5

Target Names

TRIM45

Alternative Names

FLJ13181 antibody; RING finger protein 99 antibody; RNF99 antibody; TRI45_HUMAN antibody; TRIM45 antibody; Tripartite motif containing 45 antibody; Tripartite motif containing protein 45 antibody; Tripartite motif-containing protein 45 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthetic peptide of Human TRIM45

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:2000-1:5000
IHC	1:25-1:100

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

May act as a transcriptional repressor in mitogen-activated protein kinase signaling pathway.

Gene References into Functions

These findings suggest that TRIM45 is a novel tumor suppressor that stabilizes and activates p53 in glioma. PMID: 28542145
The TRIM-FLMN protein TRIM45 directly interacts with RACK1 and negatively regulates PKC-mediated signaling pathway. PMID: 24681954
These findings suggest that TRIM45 acts as a repressor for the NF-kappaB signal and regulates cell growth. PMID: 22634006
TRIM45 may act as a new transcriptional repressor in mitogen-activated protein kinase signaling pathway PMID: 15351693

Subcellular Location

Cytoplasm. Nucleus.

Protein Families

TRIM/RBCC family

Tissue Specificity

Expressed in skeletal muscle, brain, heart and pancreas.

Database Links

HGNC: 19018

OMIM: 609318

KEGG: hsa:80263

STRING: 9606.ENSP00000256649

UniGene: Hs.301526

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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