UBE2Q2 Antibody

Code CSB-PA845153HA01HU
Size US$166
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  • Western blot
    All lanes: UBE2Q2 antibody at 2µg/ml + A431 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 43, 37, 41, 39 kDa
    Observed band size: 43 kDa

  • Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA845153HA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA845153HA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) UBE2Q2 Polyclonal antibody
Uniprot No.
Target Names
UBE2Q2
Alternative Names
LOC92912 antibody; UB2Q2_HUMAN antibody; UBE2Q2 antibody; Ubiquitin carrier protein Q2 antibody; Ubiquitin conjugating enzyme E2Q 2 antibody; Ubiquitin conjugating enzyme E2Q family member 2 antibody; Ubiquitin-conjugating enzyme E2 Q2 antibody; ubiquitin-conjugating enzyme E2Q (putative) 2 antibody; Ubiquitin-protein ligase Q2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Ubiquitin-conjugating enzyme E2 Q2 protein (1-375AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The UBE2Q2 Antibody (Product code: CSB-PA845153HA01HU) is Non-conjugated. For UBE2Q2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA845153HB01HU UBE2Q2 Antibody, HRP conjugated ELISA
FITC CSB-PA845153HC01HU UBE2Q2 Antibody, FITC conjugated
Biotin CSB-PA845153HD01HU UBE2Q2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination.
Gene References into Functions
  1. UBE2Q1 hypomethylation is associated with Colorectal Cancer. PMID: 26745068
  2. The newly characterized human gene, UBE2Q2, may have implications for the pathogenesis of acute lymphoblastic leukemia. PMID: 22642244
  3. In the 21 breast cancer cases investigated, a high increase in UBE2Q2 expression was found in 8 breast cancers (38.1%), a moderately increased UBE2Q2 expression was observed in 7 cases (33.3%), and no sig. changes were detected in 6 cases (28.6%). PMID: 20193842
  4. Found high expression levels of UBE2Q2 in human head and neck carcinoma cell lines and cancer tissues; found the level of UBE2Q2 is decreased in cell lines and cancer tissues that have resistance to CDDP or docetaxel. PMID: 19723876
  5. the novel LOC92912 gene is characterized. It is over-expressed in hypopharyngeal tumours. Its functions may be linked with the cytoskeleton; it may represent a new target for cancer therapeutics. PMID: 16300736
  6. Inhibition of the UBE2Q2 protein causes cells to undergo a prolonged prophase arrest suggesting that UBE2Q2 normally functions to antagonize an early mitotic checkpoint. PMID: 17471241

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Subcellular Location
Cytoplasm.
Protein Families
Ubiquitin-conjugating enzyme family
Tissue Specificity
Detected in hypopharyngeal head and neck squamous cell carcinoma, in tumor masses and invasive epithelium.
Database Links

HGNC: 19248

OMIM: 612501

KEGG: hsa:92912

STRING: 9606.ENSP00000267938

UniGene: Hs.23033

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