UNC5A Antibody

1. Such data indicate that cooperation between the UPR and UNC5A depletion as previously observed by ourselves in HCC patients samples may foster liver cancer development and growth. PMID: 29277614
2. UNC5A is capable of impeding autophagy and promoting HCV restriction through specific impact on virion infectivity, in a cell death-independent and DAPK-related manner. PMID: 28783179
3. FANCC interferes with UNC5A's functions in apoptosis and suggest that FANCC may participate in developmental processes through association with the dependence receptor UNC5A. PMID: 24676280
4. these data suggest an important role for UNC5A, a candidate tumor suppressor, in predicting response to DNA damage induced by chemotherapeutic drug and regulating cell death in bladder cancer PMID: 24737586
5. UNC5A is a novel transcriptional target of p53 and plays a role in p53-dependent apoptosis PMID: 20372800
6. may represent tumor suppressor that inhibit tumor extension outside the region of netrin-1 availability by inducing apoptosis PMID: 12655055
7. UNC5 orthologues define a new mechanism for both the positive (induction) and negative (suppression) regulation of apoptosis in cancer cells (review) PMID: 15573119

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HGNC: 12567

OMIM: 607869

KEGG: hsa:90249

STRING: 9606.ENSP00000332737

UniGene: Hs.33191