UTP20 Antibody

Code CSB-PA025766GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
UTP20
Alternative Names
UTP20 antibody; DRIM antibody; Small subunit processome component 20 homolog antibody; Down-regulated in metastasis protein antibody; Novel nucleolar protein 73 antibody; NNP73 antibody; Protein Key-1A6 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human UTP20
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Involved in 18S pre-rRNA processing. Associates with U3 snoRNA.
Gene References into Functions
  1. 1A6/DRIM activates Pol I transcription most likely by associating with both hALP and UBF and thereby affecting the acetylation of UBF PMID: 21151873
  2. Analysis of the relationship between DRIM gene expression and the metastatic phenotype of breast neoplasms. PMID: 14503924
  3. a single region located between amino acids 2744 and 2761 at the C-terminus is capable of nucleolar accumulation. Two basic amino acid clusters within this region are essential for nucleolar accumulation. PMID: 16458307
  4. DRIM is involved in 18S rRNA processing PMID: 17498821
Subcellular Location
Nucleus, nucleolus. Note=Colocalizes with NCL in the nucleolus.
Protein Families
UTP20 family
Tissue Specificity
Expressed in appendix, brain, colon, fetal liver, heart, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine, spleen, testis and thymus.
Database Links

HGNC: 17897

OMIM: 612822

KEGG: hsa:27340

STRING: 9606.ENSP00000261637

UniGene: Hs.295732

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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