AMOL2 Antibody

Datasheet
Code CSB-PA001679XA01HU
Product Type Polyclonal Antibody
Uniprot No. Q9Y2J4
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Homo sapiens (Human) AMOL2 protein
Raised in Rabbit
Species Reactivity Homo sapiens (Human)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP) AMOTL2 KIAA0989
Immunogen Species Homo sapiens (Human)
Gene Names AMOTL2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC.
Subcellular Location Recycling endosome
Protein Families Angiomotin family
Database Links

HGNC: 17812

OMIM: 614658

KEGG: hsa:51421

STRING: 9606.ENSP00000249883

UniGene: Hs.426312

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