ac Antibody

Code CSB-PA318709XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) ac Polyclonal antibody
Uniprot No.
Target Names
ac
Alternative Names
ac antibody; T5 antibody; CG3796Achaete-scute complex protein T5 antibody; Protein achaete antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) ac protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.
Gene References into Functions
  1. Proneural proteins Achaete and Scute associate with nuclear actin to promote formation of external sensory organs. PMID: 24190881
  2. Achate-scute is transcriptionally regulated by Suppressor of Hairy wing and Modifier of MDG4 PMID: 12783795
  3. overexpression of chn enhances expression and the formation of extra sensory organs PMID: 15703278
  4. achaete, but not scute, is dispensable for development of the peripheral nervous system of Drosophila. PMID: 16084506
  5. The general model for generation of periodic pattern in the adult leg is a process involving broad and late activation of achaete PMID: 16542648
  6. quantified the relationship between achaete-scute complex (ASC) polymorphisms and bristle number phenotypes in several new population samples PMID: 17277365
  7. Dichaete can physically interact with Ind and Vnd in the Drosophila central nervous system PMID: 17360441
  8. Studies of the AS-C has contributed to the understanding of eukaryotic gene organization and the dissection of the developmental mechanisms underlying pattern formation. PMID: 19622761

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Tissue Specificity
L(1)SC, SC and AC strongly label the presumptive stomatogastric nervous system, while ASE is more prominent in the presumptive procephalic lobe.
Database Links

KEGG: dme:Dmel_CG3796

STRING: 7227.FBpp0070071

UniGene: Dm.25370

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