Atg5 Antibody

Code CSB-PA895235XA01DLU
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Product Details

Full Product Name Rabbit anti-Drosophila melanogaster (Fruit fly) Atg5 Polyclonal antibody
Uniprot No. Q9W3R7
Target Names Atg5
Alternative Names Atg5 antibody; CG1643Autophagy protein 5 antibody; APG5-like antibody
Raised in Rabbit
Species Reactivity Drosophila melanogaster (Fruit fly)
Immunogen Recombinant Drosophila melanogaster (Fruit fly) Atg5 protein
Immunogen Species Drosophila melanogaster (Fruit fly)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables ① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time Made-to-order (14-16 weeks)

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Target Background

(From Uniprot)
Involved in autophagic vesicle formation. Conjugation with Atg12, through a ubiquitin-like conjugating system involving Atg7 as an E1-like activating enzyme and Atg10 as an E2-like conjugating enzyme, is essential for its function. The Atg12-Atg5 conjugate acts as an E3-like enzyme which is required for lipidation of Atg8 and its association to the vesicle membranes.
Gene References into Functions
  1. Studies show that the TOR signaling pathway and ATG5 and ATG7 are crucial for the regulation of cellular processes and can play various functions in different cell types in the brain. PMID: 28196106
Subcellular Location Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
Protein Families ATG5 family
Database Links

KEGG: dme:Dmel_CG1643

STRING: 7227.FBpp0071023

UniGene: Dm.33486


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