CLPC1 Antibody

Code CSB-PA863761XA01DOA
Size US$299
Image
  • Western Blot
    Positive WB detected in: recombinant protein
    All lanes:CLPC1 Antibody at 1:1000
    Secondary
    Goat polyclonal to rabbit IgG at 1/20000 dilution
    Predicted band size: 34.5 kDa
    Observed band size: 37 kDa
    Exposure time: 10s.
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) CLPC1 Polyclonal antibody
Uniprot No.
Target Names
CLPC1
Alternative Names
Chaperone protein ClpC1, chloroplastic (ATP-dependent Clp protease ATP-binding subunit ClpC homolog 1) (Casein lytic proteinase C1) (Protein DE-REGULATED CAO ACCUMULATION 1) (Protein IRON-RESCUED MUTANT 1) CLPC1 DCA1 HSP93-V IRM1 At5g50920 K3K7.7
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana (Mouse-ear cress)
Immunogen
Recombinant Arabidopsis thaliana CLPC1 protein (257-504aa )
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Molecular chaperone that hydrolyzes ATP and is associated with the chloroplast protein import apparatus. May function as the motor for chloroplast protein translocation, as translocation requires ATP hydrolysis in the stroma. May interact with a ClpP-like protease involved in degradation of denatured proteins in the chloroplast. Involved in the regulation of chlorophyll b biosynthesis through the destabilization of chlorophyllide a oxygenase (CAO) protein in response to the accumulation of chlorophyll b. Involved in leaf iron homeostasis.
Gene References into Functions
  1. Data show that the loop connecting the two halves of AtClpD N-terminal domain (NTD) is longer and covers the region which in case of AtClpC1 is thought to contribute to adaptor protein interaction. PMID: 28287170
  2. indicate that CLPC1 plays a direct or indirect role in chloroplast transcriptome homeostasis PMID: 30208840
  3. Hsp93 role in protein import and proteolysis and association with chloroplast envelope. PMID: 26586836
  4. that of the two near-identical ClpC paralogs (ClpC1 and ClpC2) in Arabidopsis chloroplasts, along with the closely related ClpD, it is ClpC1 that is the most abundant throughout leaf maturation. PMID: 24599948
  5. ClpC1 is involved in leaf Fe homeostasis, presumably via chloroplast translocation of some nuclear-encoded proteins which function in Fe transport. PMID: 20382967
  6. data suggest that overall ClpC as a stromal molecular chaperone plays a vital role in chloroplast function and leaf development and is likely involved in photosystem biogenesis. [clpC1] PMID: 15563614
  7. Study indicated that a chloroplast Clp protease is involved in regulating chlorophyll b biosynthesis through the destabilization of chlorophyllide a oxygenase protein in response to the accumulation of chlorophyll b. PMID: 17291312
  8. cpSRP54 deletion led in young leaves to up-regulation of thylakoid proteases and stromal chaperones, including ClpC. PMID: 18633119

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Subcellular Location
Plastid, chloroplast stroma. Plastid, chloroplast membrane.
Protein Families
ClpA/ClpB family, ClpC subfamily
Tissue Specificity
Highly expressed in rosette leaves. Expressed in roots, stems and inflorescences. Expressed in photosynthetic green tissues with high levels in young, developing leaf tissues.
Database Links

KEGG: ath:AT5G50920

STRING: 3702.AT5G50920.1

UniGene: At.24774

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