Code | CSB-PA340967XA01ENV |
Size | US$299 |
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In the production of the csgA polyclonal antibody, a recombinant Escherichia coli (strain K12) csgA protein segment (amino acids 45-134) is used as the immunogen to stimulate an antibody response in a rabbit. CUSABIO collects the rabbit serum and then purifies it using affinity chromatography to obtain the csgA polyclonal antibodies. The proficiency of the csgA antibody in detecting the Escherichia coli (strain K12) csgA protein is established through ELISA and WB assays, confirming its reliability for experimental applications.
The csgA protein in Escherichia coli (strain K12) is a major constituent of curli fibers, extracellular amyloid structures that serve crucial functions in bacterial physiology. CsgA is primarily involved in the formation of these curli fibers, which contribute to biofilm formation, adhesion to surfaces, and multicellular community development. The adhesion properties conferred by csgA and curli fibers enable E. coli to adhere to both biotic and abiotic surfaces, playing a role in colonization and persistence in various environments.
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KEGG: ecj:JW1025
STRING: 316385.ECDH10B_1114