DAZL Antibody

Code CSB-PA006514XA01DIL
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Product Details

Full Product Name Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) dazl Polyclonal antibody
Uniprot No. Q9YGW7
Target Names dazl
Alternative Names dazl antibody; zdazl antibody; Deleted in azoospermia-like antibody; DAZ-like protein antibody; zDazl antibody
Raised in Rabbit
Species Reactivity Danio rerio (Zebrafish) (Brachydanio rerio)
Immunogen Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) DAZL protein
Immunogen Species Danio rerio (Zebrafish) (Brachydanio rerio)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Made-to-order

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Target Data

Function RNA-binding protein, which probably plays a central role in gametogenesis in both males and females. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and promoting the translation of key transcripts.
Gene References into Functions
  1. Cortical depth and differential transport of vegetally localized dorsal and germ line determinants, Wnt8a, grip2a, and Dazl, in the zebrafish embryo have been presented. PMID: 26528729
  2. that DAZL specifically binds the HuB 3'UTR and protects the message from degradation and/or enhances HuB translation, leading to the germ cell specific expression of HuB protein. PMID: 21695151
  3. DAZL relieves miRNA-mediated repression of germline mRNAs by controlling poly(A) tail length in zebrafish PMID: 19838299
  4. Data show that DAZ-like protein directly promotes the translation of the target mRNAs in vertebrates. PMID: 12296827
Subcellular Location Cytoplasm
Protein Families RRM DAZ family
Tissue Specificity Testis and ovary specific. In ovary, it is localized in the cortex of oocytes. At the onset of embryogenesis, maternal product is located at the vegetal pole, before migrating toward blastomeres through cytoplasmic streams as early embryogenesis proceeded
Database Links

KEGG: dre:58039

STRING: 7955.ENSDARP00000052602

UniGene: Dr.81259

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