DERP1 Antibody

Code CSB-PA357315ZA01DJH
Size US$299
Image
  • Western Blot
    Positive WB detected in Recombinant protein
    All lanes: DERP1 antibody at 1:2000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 41 kDa
    Observed band size: 41 kDa
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Product Details

Full Product Name
Rabbit anti-Dermatophagoides pteronyssinus (European house dust mite) DERP1 Polyclonal antibody
Uniprot No.
Target Names
DERP1
Alternative Names
DERP1Peptidase 1 antibody; EC 3.4.22.65 antibody; Allergen Der p I antibody; Major mite fecal allergen Der p 1 antibody; allergen Der p 1 antibody
Raised in
Rabbit
Species Reactivity
Dermatophagoides pteronyssinus
Immunogen
Recombinant Dermatophagoides pteronyssinus Peptidase 1 (DERP1) (99-320AA)
Immunogen Species
Dermatophagoides pteronyssinus (European house dust mite)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Protein A/G
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Description

The DERP1 antibody is produced by inoculation of a rabbit with a recombinant Dermatophagoides pteronyssinus DERP1 (99-320aa). This induces the rabbit's B lymphocytes to produce IgG specific for the immunogen. The polyclonal DERP1 antibody is purified from the rabbit's serum by protein A/G. It is recommended for use in the detection of Dermatophagoides pteronyssinus DERP1 protein in ELISA and WB tests.

DERP1 (Der p 1) is a major allergen produced by the house dust mite Dermatophagoides pteronyssinus. It is a protein that triggers allergic reactions in susceptible individuals, particularly those with dust mite allergies. Der p 1, with its protease activity, is capable of cleaving transmembrane proteins like occludin and claudin, leading to the disruption of the bronchial epithelial barrier.

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Target Background

Function
Thiol protease, with a preference for substrates with a large hydrophobic side chain in the P2 position, or with basic residues.
Subcellular Location
Secreted.
Protein Families
Peptidase C1 family
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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