DRAXIN Antibody

Code CSB-PA822750ZA01HU
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) DRAXIN Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
AGPA3119 antibody; Chromosome 1 open reading frame 187 antibody; Dorsal inhibitory axon guidance protein antibody; Dorsal repulsive axon guidance protein antibody; DRAXI_HUMAN antibody; Draxin antibody; FLJ34999 antibody; MGC117222 antibody; Neucrin antibody; OTTHUMP00000002262 antibody; UNQ3119 antibody
Raised in
Species Reactivity
Homo sapiens
Recombinant Homo sapiens DRAXIN protein
Immunogen Species
Homo sapiens (Human)
Purification Method
Protein A/G
It differs from different batches. Please contact us to confirm it.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Tested Applications
ELISA, WB (ensure identification of antigen)
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
Gene References into Functions
  1. results suggest that draxin functions as a repulsive guidance cue for PCN migration. However, we observed no significant differences in PCN distribution between draxin(-/-) and wild type embryos. PMID: 24832731
  2. Neucrin is a unique secreted Wnt antagonist that is predominantly expressed in developing neural tissues. PMID: 19857465
Subcellular Location
Protein Families
Draxin family
Database Links

HGNC: 25054

OMIM: 612682

KEGG: hsa:374946

STRING: 9606.ENSP00000294485

UniGene: Hs.632364

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