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| Code | CSB-PA007484XA01DIL |
| Size | Enquire |
| Have Questions? | Leave a Message or Start an on-line Chat |
| Full Product Name | Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) egr1 Polyclonal antibody |
| Uniprot No. | P26632 |
| Target Names | egr1 |
| Alternative Names | egr1 antibody; krox24Early growth response protein 1 antibody; EGR-1 antibody; Zinc finger protein Krox-24 antibody |
| Raised in | Rabbit |
| Species Reactivity | Danio rerio (Zebrafish) (Brachydanio rerio) |
| Immunogen | Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) egr1 protein |
| Immunogen Species | Danio rerio (Zebrafish) (Brachydanio rerio) |
| Conjugate | Non-conjugated |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification Method | Protein A/G |
| Concentration | It differs from different batches. Please contact us to confirm it. |
| Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Form | Liquid |
| Tested Applications | ELISA, WB (ensure identification of antigen) |
| Protocols | ELISA Protocol |
| Troubleshooting and FAQs | Antibody FAQs |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Value-added Deliverables | ① 200ug * antigen (positive control); ② 1ml * Pre-immune serum (negative control); |
| Quality Guarantee | ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection; ② ELISA titer can be guaranteed 1: 64,000; ③ WB validation with antigen can be guaranteed positive; |
| Lead Time | Made-to-order (14-16 weeks) |
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| Function (From Uniprot) |
Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Mediates responses to ischemia and hypoxia; regulates the expression of proteins that are involved in inflammatory processes. Plays a role in regulating the expression of circadian clock genes. |
| Gene References into Functions |
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| Subcellular Location | Nucleus. Cytoplasm. |
| Protein Families | EGR C2H2-type zinc-finger protein family |
| Tissue Specificity | Detected in muscle and brain. |
| Database Links |
KEGG: dre:30498 STRING: 7955.ENSDARP00000054459 UniGene: Dr.144146 |
