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| Code | CSB-PA007731XA01DIL |
| Size | Enquire |
| Have Questions? | Leave a Message or Start an on-line Chat |
| Full Product Name | Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) ephb3 Polyclonal antibody |
| Uniprot No. | O13147 |
| Target Names | ephb3 |
| Alternative Names | ephb3 antibody; ek3 antibody; zek3Ephrin type-B receptor 3 antibody; EC 2.7.10.1 antibody; EPH-like kinase 3 antibody; Tyrosine-protein kinase receptor ZEK3 antibody; Fragment antibody |
| Raised in | Rabbit |
| Species Reactivity | Danio rerio (Zebrafish) (Brachydanio rerio) |
| Immunogen | Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) ephb3 protein |
| Immunogen Species | Danio rerio (Zebrafish) (Brachydanio rerio) |
| Conjugate | Non-conjugated |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification Method | Protein A/G |
| Concentration | It differs from different batches. Please contact us to confirm it. |
| Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Form | Liquid |
| Tested Applications | ELISA, WB (ensure identification of antigen) |
| Protocols | ELISA Protocol |
| Troubleshooting and FAQs | Antibody FAQs |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Value-added Deliverables | ① 200ug * antigen (positive control); ② 1ml * Pre-immune serum (negative control); |
| Quality Guarantee | ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection; ② ELISA titer can be guaranteed 1: 64,000; ③ WB validation with antigen can be guaranteed positive; |
| Lead Time | Made-to-order (14-16 weeks) |
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| Function (From Uniprot) |
Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Generally has an overlapping and redundant function with EPHB2. Like EPHB2, functions in axon guidance during development. In addition to its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and the formation of excitatory synapses. May control other aspects of development through regulation of cell migration and positioning. May play a role in early pattern formation within the developing nervous system. |
| Subcellular Location | Cell membrane; Single-pass type I membrane protein. Cell projection, dendrite. |
| Protein Families | Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily |
| Tissue Specificity | Widely expressed in the developing nervous system. |
| Database Links |
UniGene: Dr.28327 |
