EPOR Antibody

Code CSB-PA007744ZA01FQF
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Product Details

Full Product Name Rabbit anti-Canis lupus familiaris (Dog) (Canis familiaris) EPOR Polyclonal antibody
Uniprot No. Q2KL21
Target Names EPOR
Alternative Names Erythropoietin receptor (EPO-R), EPOR
Raised in Rabbit
Species Reactivity Canis lupus familiaris
Immunogen Recombinant Canis lupus familiaris EPOR protein
Immunogen Species Canis lupus familiaris (Dog) (Canis familiaris)
Conjugate Non-conjugate
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables ① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time Made-to-order (12-14 weeks)

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Target Background

Function
(From Uniprot)
Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate LYN tyrosine kinase.
Gene References into Functions
  1. sEPO-R and asEPO-R transcripts contribute to in vivo up-regulation of EPO-R protein expression in the post-pneumonectomy remaining lung. PMID: 18495932
Subcellular Location Membrane; Single-pass type I membrane protein.
Protein Families Type I cytokine receptor family, Type 1 subfamily
Database Links

KEGG: cfa:484943

STRING: 9615.ENSCAFP00000025668

UniGene: Cfa.24663

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