Recombinant Dog Erythropoietin receptor(EPOR),partial

Code CSB-EP007744DOg9
Size $2466 How to order?
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Product Details

Purity Greater than 85% as determined by SDS-PAGE.
Target Names EPOR
Uniprot No. Q2KL21
Research Area Cardiovascular
Alternative Names EPORErythropoietin receptor; EPO-R
Species Canis lupus familiaris (Dog)(Canis familiaris)
Source E.coli
Expression Region 25-250aa
Target Protein Sequence ASLPKPLDPKFESKAALLAARAPEELLCFTERLEDLVCFWEEAASAGVGPDNYSFFYQLEGEPWKTCSLHQAPTTRGAVRFWCSLPTADTSSFVPLELRATAVSSGALLYRRIIHINEVVLLDPPAGLLARRADEGGHVVLRWLPPPGAPVASLIRYEVNISGSVAGGSQKVEILDGRTECVLSNLRGGTRYTFMVRARMAEPSFGGFWSAWSEPASLLTASDLDP
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
Mol. Weight 36.4 kDa
Protein Length Partial
Tag Info N-terminal 6xHis-GB1-tagged and C-terminal 6xHis-tagged
Form Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting
and FAQs
Protein FAQs
Storage Condition Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time 13-23 business days
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA Please contact us to get it.

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Target Background

Function
Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate LYN tyrosine kinase.
Gene References into Functions
  1. sEPO-R and asEPO-R transcripts contribute to in vivo up-regulation of EPO-R protein expression in the post-pneumonectomy remaining lung. PMID: 18495932
Subcellular Location Membrane; Single-pass type I membrane protein.
Protein Families Type I cytokine receptor family, Type 1 subfamily
Database Links

KEGG: cfa:484943

STRING: 9615.ENSCAFP00000025668

UniGene: Cfa.24663

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Address
7505 Fannin St. Ste 610-312, Houston, TX 77054, USA
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