fbf-1 Antibody

1. It was concluded that FBF1 is a key functional transition fibre component that actively facilitates the ciliary entry of assembled IFT machinery. PMID: 24231678
2. Data show that CPB-1 (cytoplasmic polyadenylation element binding protein homolog-1) alters the affinity of FBF (fem-3 mRNA binding factor) for specific RNA sequences. PMID: 23159558
3. Data indicate that a 10-amino-acid region in germline development defective-3 (GLD-3) is required for fem-3 binding factor (FBF) binding, while a 7-amino-acid loop in FBF between PUF repeats 7 and 8 is necessary for GLD-3 binding. PMID: 23159559
4. Here, the authors report that FBF/Pumilio, a conserved RNA-binding protein, promotes self-renewal of germline stem cells by repressing CKI-2(Cip/Kip), a Cyclin E/Cdk2 inhibitor. PMID: 21822213
5. The Puf RNA-binding proteins FBF-1 and FBF-2 inhibit the expression of synaptonemal complex proteins in germline stem cells. PMID: 20431119
6. fbf-1 regulates the size of the mitotic region in helminth germ cells. PMID: 15525531
7. FBF may coordinately repress sperm-specifying mRNAs to direct oogenesis and it represses the fog-1 mRNA to maintain FOG-1 at a low level appropriate for proliferation PMID: 16000383
8. all fbf-1 puf-8 double mutants fail in the hermaphrodite sperm/oocyte switch PMID: 16037210
9. A structural distortion in the central region of FBF imposes the requirement for an additional nucleotide to effect messenger RNA binding, thus defining its specificity. PMID: 16244662
10. Fbf-1 redundantly inhibits primary vulval cell fate specification in two distinct pathways acting in the soma and in the germline PMID: 16908630
11. Results show that the RNA-binding PUF protein FBF-1 is required in the adult olfactory sensory neurons of C. elegans for adaptation. PMID: 19146813

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KEGG: cel:CELE_H12I13.4

STRING: 6239.H12I13.4

UniGene: Cel.23295