FDXR Antibody

Code CSB-PA008575ZA01BO
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Product Details

Full Product Name
Rabbit anti-Bos taurus (Bovine) FDXR Polyclonal antibody
Uniprot No.
Target Names
FDXR
Alternative Names
FDXR antibody; ADXRNADPH:adrenodoxin oxidoreductase antibody; mitochondrial antibody; AR antibody; Adrenodoxin reductase antibody; EC 1.18.1.6 antibody; Ferredoxin--NADP(+) reductase antibody; Ferredoxin reductase antibody
Raised in
Rabbit
Species Reactivity
Bos taurus
Immunogen
Recombinant Bos taurus FDXR protein
Immunogen Species
Bos taurus (Bovine)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Function
Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.
Gene References into Functions
  1. We constructed cDNA including genes of the bovine cholesterol hydroxylase/lyase (CHL) system proteins-cytochrome P450scc (CYP11A1), adrenodoxin (Adx) and adrenodoxin reductase (AdR), that are fused into a single ORF using FMDV 2A nucleotide sequences. PMID: 28799023
  2. S. pombe is either very robust to mitochondrial reactive oxygen species (ROS) production or does not undergo apoptotic cell death in response to mitochondrial ROS at all. PMID: 17885803
Subcellular Location
Mitochondrion inner membrane; Peripheral membrane protein.
Protein Families
Ferredoxin--NADP reductase type 1 family
Tissue Specificity
Detected in adrenal cortex and corpus luteum (at protein level).
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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