FXN Antibody

Code CSB-PA810224ZA01MOV
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Product Details

Full Product Name
Rabbit anti-Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) FXN Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
FXN antibody; FRDA1 antibody; QnpA-13971 antibody; Frataxin antibody; mitochondrial antibody; Fxn antibody; EC 1.16.3.1) [Cleaved into: Frataxin intermediate form; Frataxin mature form] antibody
Raised in
Rabbit
Species Reactivity
Macaca fascicularis
Immunogen
Recombinant Macaca fascicularis FXN protein
Immunogen Species
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Function
Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1.
Subcellular Location
Cytoplasm, cytosol. Mitochondrion.
Protein Families
Frataxin family
Database Links

KEGG: mcf:102120656

UniGene: Mfa.6270

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