FZR1 Antibody

^{Rare Species}

Datasheet

Code	CSB-PA845079XA01DOA
Size	US$299
Image	Western Blot Positive WB detected in: recombinant protein All lanes: FZR1 Antibody at 1:1000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 34 kDa Observed band size: 34 kDa
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Target Background

Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) FZR1 Polyclonal antibody

Uniprot No.

Q8VZS9

Target Names

FZR1

Alternative Names

Protein FIZZY-RELATED 1 (Cell cycle switch protein CCS52A2) FZR1 CCS52A2 CDH1-1 At4g11920 T26M18.130

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana FZR1 protein (1-280aa)

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Activator protein that regulates the ubiquitin ligase activity and substrate specificity of the anaphase promoting complex/cyclosome (APC/C). Required for meristem organization and maintenance of quiescent center identity and stem cells.

Gene References into Functions

The data illustrate cooperative activity of the APC/C(CCS52A1) and APC/C(CCS52A2) complexes during root and trichome development, but functional interdependency during leaf development. Furthermore, we found APC/C(CCS52A1) activity to control CCS52A2 expression. We conclude that interdependency of CCS52A-controlled APC/C activity is controlled in a tissue-specific manner. PMID: 28698355
A ccs52A2 mutation did not affect the level or pattern of cyclin B1;1 expression, indicating that CCS52A2 does not mediate the effect of auxin on cyclin B1;1. PMID: 26662023
Findings support both complementary and dose-dependent actions for the Arabidopsis CCS52A isoforms in plant development and demonstrate that elevated ectopic CCS52A expression positively correlates with organ size, opening a route to higher biomass production. [CCS52A2] PMID: 23528034
The CCS52A2 gene is a mediator that functions together with meristematic genes to regulate meristem organization. PMID: 22873486
CCS52A2 acts directly in the distal region of the root meristem to control identity of the quiescent center (QC) cells and stem cell maintenance. PMID: 19553203

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Subcellular Location

Nucleus.

Protein Families

WD repeat CDC20/Fizzy family

Tissue Specificity

Expressed in the root tip, predominantly in the root cap, quiescent center cells, surrounding stem cells and columella.

Database Links

KEGG: ath:AT4G11920

STRING: 3702.AT4G11920.1

UniGene: At.27160

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Cell cycle Ubiquitin mediated proteolysis Excitatory synapse pathway

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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FZR1 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background