Fizzy-related protein homolog is a protein in humans that is encoded by FZR1 gene. Substrate-specific adapter for the anaphase promoting complex/cyclosome (APC/C) E3 ubiquitin-protein ligase complex. Associates with the APC/C in late mitosis, in replacement of CDC20, and activates the APC/C during anaphase and telophase. The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely. At the G1/S transition FZR1 is phosphorylated, leading to its dissociation from the APC/C. Following DNA damage, it is required for the G2 DNA damage checkpoint.
The following FZR1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
FZR1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA009113GA01HU | FZR1 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA892473LA01HU | FZR1 Antibody |
Human | ELISA, WB, IHC |
CSB-PA892473LB01HU | FZR1 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA892473LC01HU | FZR1 Antibody, FITC conjugated |
Human | |
CSB-PA892473LD01HU | FZR1 Antibody, Biotin conjugated |
Human | ELISA |
FZR1 Antibodies for Arabidopsis thaliana (Mouse-ear cress)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA845079XA01DOA | FZR1 Antibody |
Arabidopsis thaliana | ELISA, WB |
FZR1 Proteins for Arabidopsis thaliana (Mouse-ear cress)
Code | Product Name | Source |
---|---|---|
CSB-YP845079DOA CSB-EP845079DOA CSB-BP845079DOA CSB-MP845079DOA CSB-EP845079DOA-B |
Recombinant Arabidopsis thaliana Protein FIZZY-RELATED 1 (FZR1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FZR1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP889934MO CSB-EP889934MO CSB-BP889934MO CSB-MP889934MO CSB-EP889934MO-B |
Recombinant Mouse Fizzy-related protein homolog (Fzr1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FZR1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP892473HU CSB-BP892473HU CSB-MP892473HU CSB-EP892473HU-B |
Recombinant Human Fizzy-related protein homolog (FZR1) |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP892473HU | Recombinant Human Fizzy-related protein homolog (FZR1) |
E.coli |