GPX2 Antibody

Code CSB-PA009867XA01SVG
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Product Details

Full Product Name Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) GPX2 Polyclonal antibody
Uniprot No. P38143
Target Names GPX2
Alternative Names GPX2 antibody; YBR244W antibody; YBR1632Glutathione peroxidase-like peroxiredoxin 2 antibody; EC 1.11.1.15 antibody; Glutathione peroxidase homolog 2 antibody; GPx 2 antibody
Raised in Rabbit
Species Reactivity Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) GPX2 protein
Immunogen Species Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables ① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time Made-to-order (14-16 weeks)

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Target Background

Function
(From Uniprot)
Glutathione peroxidase-like protein that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress. Plays an important role in the oxidative stress-induced response in the presence of Ca(2+). Has peroxidase activity using preferentially thioredoxin as a reducing power. The redox state of the mitochondrial GPX2 is regulated by TRX1 and TRX2 (cytoplasmic thioredoxin), and by TRX3 (mitochondrial matrix thioredoxin). Involved in sporulation.
Gene References into Functions
  1. Gpx2 was found to exist in the cytoplasm and mitochondria. PMID: 21763276
  2. determination that Gpx2 codes for an atypical 2-Cys peroxiredoxin and is likely to play an important role in the protection of cells from oxidative stress in the presence of Ca2+ PMID: 16251189
Subcellular Location Cytoplasm. Nucleus. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein Families Glutathione peroxidase family
Database Links

KEGG: sce:YBR244W

STRING: 4932.YBR244W

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