HDAC1 Antibody

Code CSB-PA213658XA01OFG
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Product Details

Full Product Name
Rabbit anti-Oryza sativa subsp. japonica (Rice) HDAC1 Polyclonal antibody
Uniprot No.
Target Names
HDAC1
Alternative Names
HDAC1 antibody; HDA702 antibody; Os06g0583400 antibody; LOC_Os06g38470 antibody; P0498C03.28-1 antibody; Histone deacetylase 1 antibody; OsHDAC1 antibody; EC 3.5.1.98 antibody
Raised in
Rabbit
Species Reactivity
Oryza sativa subsp. japonica (Rice)
Immunogen
Recombinant Oryza sativa subsp. japonica (Rice) HDAC1 protein
Immunogen Species
Oryza sativa subsp. japonica (Rice)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (Probable). Regulates negatively the expression of the NAC48/NAC6 gene that controls root growth in seedlings. Epigenetically represses the expression of NAC48/NAC6 by deacetylating 'Lys-9' (H3K9ac), 'Lys-14' (H3K14ac) and 'Lys-18' (H3K18ac) of histone H3, and 'Lys-5' (H4K5ac), 'Lys-12' (H4K12ac) and 'Lys-16' (H4K16ac) of histone H4. Functions in the regulation of gene expression in the whole genome. Acts as chromatin remodeling regulator to promote the formation of a repressive chromatin state. Functions with MODD via its interaction with TPR3, to down-regulates the histone acetylation level at BZIP46 target genes. BZIP46 is a positive regulator of abscisic acid (ABA) signaling and drought stress tolerance.
Gene References into Functions
  1. OsHDAC1 epigenetically regulates the OsNAC6 gene, and that this is primarily responsible for the alteration of root development in rice seedlings. PMID: 19453457
Subcellular Location
Nucleus.
Protein Families
Histone deacetylase family, HD Type 1 subfamily
Tissue Specificity
Expressed in roots and leaves.
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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