ISM1 Antibody

Code CSB-PA011850ZA01HU
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ISM1 Polyclonal antibody
Uniprot No.
Target Names
ISM1
Alternative Names
ISM1 antibody; C20orf82 antibody; ISM antibody; Isthmin-1 antibody
Raised in
Rabbit
Species Reactivity
Homo sapiens
Immunogen
Recombinant Human Isthmin-1 (ISM1) (30-464AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Protein A/G
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order

Customer Reviews and Q&A

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Target Background

Function
Acts as an angiogenesis inhibitor.
Gene References into Functions
  1. Our study demonstrates a successful pipeline from CNV identification of a candidate gene to functional validation in a vertebrate model system, and reveals Isthmin 1 as both a new human clefting locus as well as a key craniofacial patterning gene. PMID: 29162626
  2. Given that ISM1 has been reported to have anti-angiogenic properties, these observations suggest that ISM1 is a mediator of lymphocyte effector functions and may participate in both innate and acquired immune responses. PMID: 24956034
  3. Isthmin unexpectedly has both a pro-survival and death-promoting effect on endothelial cells depending on its physical state. PMID: 21544092
Subcellular Location
Secreted.
Protein Families
Isthmin family
Database Links

HGNC: 16213

OMIM: 615793

KEGG: hsa:140862

STRING: 9606.ENSP00000262487

UniGene: Hs.559353

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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