Camk2b Antibody

1. Region-specific overexpression of betaCaMKII in dentate gyrus (DG) impairs behavioral flexibility, and severely attenuates the NMDAR-dependent long-term depression (LTD) in DG medial perforant path, which is further confirmed by the diminished AMPAR internalization and dephosphorylation during LTD. PMID: 27993520
2. data suggest that phosphorylation of CaMKIIbeta through the mGluR/IP3R1/PKC signaling pathway represses excessive spine formation and elongation in mature Purkinje cells. PMID: 28607044
3. The molecular, temporal and region-specific requirements of the CAMK2B in mouse locomotion have been described. PMID: 27244486
4. Study used an unbiased semiquantitative proteomics approach to identify biologically relevant phosphorylation sites on both CaMKIIa and CaMKIIb PMID: 25650780
5. CaMKK/CaMK IV pathway is a key endogenous protective mechanism in cerebral ischemia. PMID: 23868268
6. Our data point toward a critical role of CaMKIIbeta in regulating oligodendrocyte maturation and CNS myelination via an actin-cytoskeleton-regulatory mechanism PMID: 23785157
7. Muscle-specific CamkIIss isoform is critical for receptor recycling and may provide a mechanism by which the postsynaptic acetylcholine receptor density is maintained at the neuromuscular junction in vivo. PMID: 20844140
8. is expressed in motor neurons during axon outgrowth and is part of slow axonal transport. PMID: 11891785
9. accumulated in the nuclei of brain cells by pentylenetetrazol-mediated seizure via cellular mechanisms other than transcriptional and post-transcriptional regulation PMID: 11897160
10. Ca/CaMK II activation plays an important role in the transmission of GnRH signals from the plasma membrane to the LH subunit genes. PMID: 12746302
11. Expression of an active form of CaMKII beta after 1 day of T cell activation enhances initial proliferation and cytotoxic T cell activity, but induces profound unresponsiveness to peptide restimulation. PMID: 15843557
12. activated CaMKII directly phosphorylated the recombinant COOH-terminal region of FAK at a residue equivalent to Ser-843 PMID: 15845548
13. CaM kinase IIdelta2 was involved in the GnRH-induced activation of MAP kinase in GT1-7 cells. PMID: 17706588
14. betaCaMKII activity in the dentate gyrus selectively impaired long-term potentiation in the dentate perforant path, but not in the CA1 Schaffer collateral pathway. PMID: 17913888
15. We found that betaCaMKII, the predominant CaMKII isoform of the cerebellum, is important for controlling the direction of plasticity at the parallel fiber-Purkinje cell synapse PMID: 19503086
16. Deletion studies indicated three important parts of beta CaM kinase II: beta-specific insertion 2, the association domain, and the oligomeric form; all 3 play an important role in its cellular distribution. PMID: 11532017

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KEGG: mmu:12323

UniGene: Mm.439733