Lgmn Antibody

Datasheet
Code CSB-PA012903ZA01MO

Product Details

Full Product Name Rabbit anti-Mus musculus (Mouse) Lgmn Polyclonal antibody
Uniprot No. O89017
Target Names Lgmn
Alternative Names Legumain (EC 3.4.22.34) (Asparaginyl endopeptidase) (Protease, cysteine 1), Lgmn, Prsc1
Raised in Rabbit
Species Reactivity Mus musculus
Immunogen Recombinant Mouse Legumain (Lgmn) (18-325AA)
Immunogen Species Mus musculus (Mouse)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Made-to-order
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Target Data

Function Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation.
Subcellular Location Lysosome
Protein Families Peptidase C13 family
Tissue Specificity Detected in kidney proximal tubules (at protein level). Ubiquitous. Particularly abundant in kidney and placenta.
Database Links

KEGG: mmu:19141

STRING: 10090.ENSMUSP00000021607

UniGene: Mm.17185

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