MCM2 Antibody

Code CSB-PA926656XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) MCM2 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
MCM2 antibody; At1g44900 antibody; T12C22.19 antibody; DNA replication licensing factor MCM2 antibody; EC 3.6.4.12 antibody; Minichromosome maintenance protein 2 antibody; AtMCM2 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana MCM2 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells. May play a crucial role in the control of de-differentiation and cell proliferation processes required for lateral root formation. Is essential for embryo development. Is involved in the geminivirus mungbean yellow mosaic virus (MYMV) DNA replication, presumably in conjunction with other host factors.
Gene References into Functions
  1. Authors demonstrated an interaction between mungbean yellow mosaic India virus-Rep and the host factor Arabidopsis thaliana MCM2. PMID: 23242774
  2. Disruption of AtMCM2 is lethal at a very early stage of embryogenesis, whereas its over-expression results in reduced growth and inhibition of endoreduplication. [MCM2] [Minichromosome maintenance protein 2] PMID: 19650778
Subcellular Location
Nucleus.
Protein Families
MCM family
Tissue Specificity
Expressed in root apical meristem, lateral root meristem primordia, leaf primordia, shoot apical meristem and flower buds.
Database Links

KEGG: ath:AT1G44900

STRING: 3702.AT1G44900.1

UniGene: At.5390

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