MCM2

DNA replication licensing factor MCM2 is a protein in humans that is encoded by MCM2 gene. Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division. Plays a role in terminally differentiated hair cells development of the cochlea and induces cells apoptosis.

The following MCM2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

MCM2 Antibodies

MCM2 Proteins

MCM2 Antibodies

MCM2 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA013590LC01HU	MCM2 Antibody, FITC conjugated	Human
CSB-PA013590LA01HU	MCM2 Antibody	Human	ELISA, WB, IHC, IF
CSB-PA013590GA01HU	MCM2 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA016903	MCM2 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA000999	MCM2 Antibody	Human,Mouse	WB, IHC, IF, ELISA
CSB-PA578532	MCM2 Antibody	Human,Mouse	ELISA,WB,IHC
CSB-PA033980	MCM2 Antibody	Human,Mouse	ELISA,IHC

MCM2 Antibodies for Arabidopsis thaliana (Mouse-ear cress)

Code	Product Name	Species Reactivity	Application
CSB-PA926656XA01DOA	MCM2 Antibody	Arabidopsis thaliana	ELISA, WB (ensure identification of antigen)

MCM2 Antibodies for Drosophila melanogaster (Fruit fly)

Code	Product Name	Species Reactivity	Application
CSB-PA013590XA01DLU	Mcm2 Antibody	Drosophila melanogaster (Fruit fly)	ELISA, WB (ensure identification of antigen)

MCM2 Antibodies for Oryza sativa subsp. japonica (Rice)

Code	Product Name	Species Reactivity	Application
CSB-PA229690XA01OFG	MCM2 Antibody	Oryza sativa subsp. japonica (Rice)	ELISA, WB (ensure identification of antigen)

MCM2 Antibodies for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Code	Product Name	Species Reactivity	Application
CSB-PA013590XA01SVG	MCM2 Antibody	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	ELISA, WB (ensure identification of antigen)

MCM2 Antibodies for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Code	Product Name	Species Reactivity	Application
CSB-PA013590XA01SXV	mcm2 Antibody	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ELISA, WB (ensure identification of antigen)

MCM2 Proteins

MCM2 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP013590MO CSB-EP013590MO CSB-BP013590MO CSB-MP013590MO CSB-EP013590MO-B	Recombinant Mouse DNA replication licensing factor MCM2 (Mcm2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MCM2 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP013590HU CSB-BP013590HU CSB-MP013590HU CSB-EP013590HU-B	Recombinant Human DNA replication licensing factor MCM2 (MCM2), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP013590HU	Recombinant Human DNA replication licensing factor MCM2 (MCM2)	E.coli

MCM2 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Code	Product Name	Source
CSB-YP013590SVG CSB-EP013590SVG CSB-BP013590SVG CSB-MP013590SVG CSB-EP013590SVG-B	Recombinant Saccharomyces cerevisiae DNA replication licensing factor MCM2 (MCM2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MCM2 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Code	Product Name	Source
CSB-YP013590SXV CSB-EP013590SXV CSB-BP013590SXV CSB-MP013590SXV CSB-EP013590SXV-B	Recombinant Schizosaccharomyces pombe DNA replication licensing factor mcm2 (mcm2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MCM2 Proteins for Drosophila melanogaster (Fruit fly)

Code	Product Name	Source
CSB-YP013590DLU CSB-EP013590DLU CSB-BP013590DLU CSB-MP013590DLU CSB-EP013590DLU-B	Recombinant Drosophila melanogaster DNA replication licensing factor Mcm2 (Mcm2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MCM2 Proteins for Xenopus laevis (African clawed frog)

Code	Product Name	Source
CSB-YP013590XBE CSB-EP013590XBE CSB-BP013590XBE CSB-MP013590XBE CSB-EP013590XBE-B	Recombinant Xenopus laevis DNA replication licensing factor mcm2 (mcm2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MCM2 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

Code	Product Name	Source
CSB-YP728539XBF CSB-EP728539XBF CSB-BP728539XBF CSB-MP728539XBF CSB-EP728539XBF-B	Recombinant Xenopus tropicalis DNA replication licensing factor mcm2 (mcm2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Popular Pathways

Apoptosis

Breast Cancer

Autophagy

Hippo Signaling Pathway

Wnt Signaling Pathway

Hippo signaling pathway

TGF-beta signaling pathway

Apoptosis mediated by mitochondria The Overview of Hippo Signaling Pathway The Overview of Autophagy Crosstalk Between Autophagy and Apoptosis The Overview of Wnt Signaling Pathway The Overview of Breast Cancer: Related Signaling Pathways, Therapeutic Targets The overview of TGF-β signaling pathway PI3K-Akt Signaling Pathway and Cancer Apoptosis mediated by endoplasmic reticulum Apoptosisi mediated by death receptor Aesthetic Appreciation of Apoptosis Signal Pathway An Overview of Cell Death: Necrosis and Apoptosis Do You Really Know TGF-β Superfamily? Double-Edged Sword: TGF-β The Overview of PI3-Alt Signaling Pathway How to Inquire and Utilize the Signal Pathway on KEGG LPS/TLR4 Signal Transduction Pathway Epigenetic Histone Modifications Pathway What A Paradoxical TNF Signaling Pathway-Based on Different Receptors The Overview of Fc Receptors- Classification, Related Signaling Pathways and Application