MLH1 Antibody

Rare Species
Code CSB-PA819964XA01DOA
Size US$299
Image
  • Western Blot
    Positive WB detected in: recombinant protein
    All lanes:MLH1 Antibody at 1:1000
    Secondary
    Goat polyclonal to rabbit IgG at 1/20000 dilution
    Predicted band size: 33 kDa
    Observed band size: 33 kDa
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) MLH1 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
DNA mismatch repair protein MLH1 (MutL protein homolog 1) (Protein MUTL-HOMOLOGUE 1) (AtMLH1) MLH1 At4g09140 F23J3.170 T8A17.9
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana MLH1 protein (31-260aa)
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Involved in DNA mismatch repair (MMR), correcting insertion-deletion loops (IDLs) resulting from DNA replication, DNA damage or from recombination events between non-identical sequences during meiosis. Component of the MutLbeta heterodimer, which probably forms a ternary complex with the MutSbeta heterodimer that initially recognizes the DNA mismatches. This complex is thought to be responsible for directing the downsteam MMR events, including strand discrimination, excision, and resynthesis. Plays a major role in promoting meiotic crossing-over and is involved in maintaining the genetic stability of simple sequence repeats by correction of frameshift intermediates.
Gene References into Functions
  1. required for recombination and acts to limit recombination between diverged sequences PMID: 17559505
Subcellular Location
Nucleus.
Protein Families
DNA mismatch repair MutL/HexB family
Tissue Specificity
Ubiquitous.
Database Links

KEGG: ath:AT4G09140

STRING: 3702.AT4G09140.1

UniGene: At.671

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