MLH1 Antibody

Datasheet
Code CSB-PA819964XA01DOA
Product Type Polyclonal Antibody
Uniprot No. Q9ZRV4
Delivery Make-to-order
Immunogen Recombinant Arabidopsis thaliana MLH1 protein
Raised in Rabbit
Species Reactivity Arabidopsis thaliana
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugate
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias DNA mismatch repair protein MLH1 (MutL protein homolog 1) (Protein MUTL-HOMOLOGUE 1) (AtMLH1) MLH1 At4g09140 F23J3.170 T8A17.9
Immunogen Species Arabidopsis thaliana (Mouse-ear cress)
Protocols ELISA Protocol
Gene Names MLH1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Involved in DNA mismatch repair (MMR), correcting insertion-deletion loops (IDLs) resulting from DNA replication, DNA damage or from recombination events between non-identical sequences during meiosis. Component of the MutLbeta heterodimer, which probably forms a ternary complex with the MutSbeta heterodimer that initially recognizes the DNA mismatches. This complex is thought to be responsible for directing the downsteam MMR events, including strand discrimination, excision, and resynthesis. Plays a major role in promoting meiotic crossing-over and is involved in maintaining the genetic stability of simple sequence repeats by correction of frameshift intermediates.
Subcellular Location Nucleus
Protein Families DNA mismatch repair MutL/HexB family
Tissue Specificity Ubiquitous.
Database Links

KEGG: ath:AT4G09140

STRING: 3702.AT4G09140.1

UniGene: At.671

Pathway DNA repair pathway

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