MRE11 Antibody

Code CSB-PA893132XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) MRE11 Polyclonal antibody
Uniprot No.
Target Names
MRE11
Alternative Names
MRE11 antibody; At5g54260 antibody; MDK4.8 antibody; Double-strand break repair protein MRE11 antibody; AtMre11 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana MRE11 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
Gene References into Functions
  1. Functional and full-length AtMRE11 is essential for activation of the cell cycle arrest, transcriptional regulation and DNA repair upon induction of double strand break (DSB). PMID: 27007017
  2. TAF1 interaction with MRE11 is mediated by the C-terminal bromodomain of TAF1. PMID: 26358508
  3. functions of MRE11 in Arabidopsis meiosis PMID: 24205310
  4. The Atdfo Atmre11 double mutant had no such chromosome fragmentation, indicating that AtDFO is required for DNA double-strand break (DSB) formation. PMID: 22694475
  5. The cytological behavior of a possible early recombination nodules component, MRE11, a protein that is important for the repair of the numerous, programmed deoxyribonucleic acid double-strand breaks (DSBs) that occur early in the meiotic prophase.[ PMID: 18293007

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Subcellular Location
Nucleus.
Protein Families
MRE11/RAD32 family
Database Links

KEGG: ath:AT5G54260

STRING: 3702.AT5G54260.1

UniGene: At.493

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