| Code | CSB-PA339648XA01SVG |
| Size | Pls inquire |
| Have Questions? | Leave a Message or Start an on-line Chat |
| Full Product Name | Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) OMA1 Polyclonal antibody |
| Uniprot No. | P36163 |
| Target Names | OMA1 |
| Alternative Names | OMA1; YKR087C; YKR407; Mitochondrial metalloendopeptidase OMA1 |
| Raised in | Rabbit |
| Species Reactivity | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
| Immunogen | Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) OMA1 protein |
| Immunogen Species | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
| Conjugate | Non-conjugated |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification Method | Protein A/G |
| Concentration | It differs from different batches. Please contact us to confirm it. |
| Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Form | Liquid |
| Tested Applications | ELISA, WB (ensure identification of antigen) |
| Protocols | ELISA Protocol |
| Troubleshooting and FAQs | Antibody FAQs |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Value-added Deliverables | ① 200ug * antigen (positive control); ② 1ml * Pre-immune serum (negative control); |
| Quality Guarantee | ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection; ② ELISA titer can be guaranteed 1: 64,000; ③ WB validation with antigen can be guaranteed positive; |
| Lead Time | Made-to-order (14-16 weeks) |
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| Function (From Uniprot) |
Protease that is part of the quality control system in the inner membrane of mitochondria. Activated in response to various mitochondrial stress, leading to the proteolytic cleavage of target proteins, such as OXA1 and COX1. Cleaves and thereby promotes the turnover of mistranslated or misfolded membrane proteins. Cleaves the misfolded multi-pass membrane protein OXA1. Involved in quality control of cytochrome oxidase assembly: mediates the cleavage of COX1 in cells lacking COA2. Required for the stability of the respiratory supercomplexes. Required for TOR signaling. |
| Gene References into Functions |
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| Subcellular Location | Mitochondrion inner membrane; Single-pass membrane protein. |
| Protein Families | Peptidase M48 family |
| Database Links |
KEGG: sce:YKR087C STRING: 4932.YKR087C |
