Omega-hexatoxin-Hv1a Antibody

Code CSB-PA347842ZA01HAD
Size US$299
Image
  • Western Blot
    Positive WB detected in Recombinant protein
    All lanes: Omega-hexatoxin-Hv1a antibody at 1:2000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 25 kDa
    Observed band size: 25 kDa
The Latest Promotion Free Antibody trial simple
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Uniprot No.
Target Names
N/A
Alternative Names
Omega-hexatoxin-Hv1a (Omega-HXTX-Hv1a) (Omega-atracotoxin-Hv1a) (AcTx-Hv1) (Omega-AcTx-Hv1a)
Species Reactivity
Hadronyche versuta
Immunogen
Recombinant Hadronyche versuta Omega-hexatoxin-Hv1a protein (1-37aa )
Immunogen Species
Hadronyche versuta (Blue mountains funnel-web spider) (Atrax versutus)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Protein G
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Description

To create the Omega-hexatoxin-Hv1a polyclonal antibody, a rabbit was immunized with the recombinant Hadronyche versuta Omega-hexatoxin-Hv1a protein (1-37aa ). Afterward, the Omega-hexatoxin-Hv1a antibody was extracted from the rabbit serum and purified using protein G. This specific Omega-hexatoxin-Hv1a antibody is ideal for detecting the Omega-hexatoxin-Hv1a protein of Hadronyche versuta in ELISA and WB experiments.

The Omega-hexatoxin-Hv1a protein, found in the venom of the Australian funnel-web spider species Hadronyche versuta, mainly functions to act as a neurotoxin. This protein specifically targets and blocks certain ion channels in the nervous system, particularly those involved in the transmission of pain signals. By inhibiting these ion channels, the Omega-hexatoxin-Hv1a protein can cause paralysis and potentially lead to death in its prey or potential threats.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Reversibly and voltage-independently blocks both mid-low- (M-LVA) and high-voltage-activated (HVA) calcium channels in cockroach DUM neurons. Lethal to many insect species but not toxic to mammals. May target the insect high-voltage-activated calcium channel Dmca1D. Also inhibits acarines calcium channels. An extremely high toxin concentration partially inhibits Cav1.2/CACNA1C, Cav2.1/CACNA1A and Cav2.2/CACNA1B calcium channel of rats. As for omega-AcTx-Hv2a, the phenotypic effect of injection of this toxin into lone star ticks (Amblyomma americanum) is curling of all eight legs into closed loops.
Subcellular Location
Secreted.
Protein Families
Shiva superfamily, Omega toxin family
Tissue Specificity
Expressed by the venom gland.
icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1