Pdk1 Antibody

Code CSB-PA894764XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Pdk1 Polyclonal antibody
Uniprot No.
Target Names
Pdk1
Alternative Names
Pdk1 antibody; Pk61C antibody; CG1210 antibody; 3-phosphoinositide-dependent protein kinase 1 antibody; dPDK-1 antibody; EC 2.7.11.1 antibody; Serine/threonine-protein kinase 61C antibody; dSTPK61 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Pdk1 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Serine/threonine kinase required for embryonic development. Inhibits apoptosis. Acts in the insulin receptor transduction pathway which regulates cell growth and organ size, by phosphorylating and activating Akt1 and S6k. May be involved in axonal pathfinding and synaptogenesis, and in spermatogenesis.
Gene References into Functions
  1. PDK1 is also a presynaptic protein, though it is distributed more broadly. PMID: 21930778
  2. dS6K activity is dependent on the Drosophila homologue of the phosphoinositide-dependent protein kinase 1, dPDK1 PMID: 11862217
Subcellular Location
Cytoplasm.
Protein Families
Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDPK1 subfamily
Database Links

KEGG: dme:Dmel_CG1210

STRING: 7227.FBpp0305420

UniGene: Dm.7033

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