Ras85D Antibody

1. In conclusion, Ras(V12)-modified caspases initiate a feedback amplification loop involving tumorous epithelial cells and macrophage-like immune cells that is necessary for uncontrolled tumor growth and invasive behavior. PMID: 28853394
2. Thus, our current work provides a novel mechanism of pupal size determination by microRNAs during Drosophila melanogaster metamorphosis. PMID: 27733364
3. Oncogenic Ras stimulates Eiger/TNF exocytosis to promote growth. PMID: 25411211
4. Inhibition of Ras1 signaling leads to reduced Appl expression, whereas constitutive activation drives ectopic Appl expression. PMID: 23178937
5. Data show that the ras1(R68Q) mutant is homozygous viable but causes various developmental defects associated with elevated Ras signaling. PMID: 21858158
6. Results conclude that the membrane association of Drosophila Ras1 is not required for eye development. PMID: 20937772
7. interaction between Ras(V12) and scrib(-) clones involves JNK signalling propagation and JNK-induced upregulation of JAK/STAT-activating cytokines, a compensatory growth mechanism for tissue homeostasis PMID: 20072127
8. In the Drosophila eye, Ras may protect cells from apoptosis by inhibiting both JNK and Hid activities. Surprisingly, reducing Ras activity in the wing, however, does not cause apoptosis but rather affects cell and organ size. PMID: 19840402
9. Ras activity in the prothoracic gland regulates body size and the duration of each larval stage by regulating ecdysone release. PMID: 16182526

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KEGG: dme:Dmel_CG9375

STRING: 7227.FBpp0081600

UniGene: Dm.4812