UPF1 Antibody

Datasheet

Code	CSB-PA875473XA01DOA
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Target Background

Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) UPF1 Polyclonal antibody

Uniprot No.

Q9FJR0

Target Names

UPF1

Alternative Names

UPF1 antibody; LBA1 antibody; At5g47010 antibody; MQD22.15 antibody; Regulator of nonsense transcripts 1 homolog antibody; EC 3.6.4.- antibody; ATP-dependent helicase UPF1 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana UPF1 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (premature termination codon PTC) by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. Eliminates the production of nonsense-containing RNAs (ncRNAs). Required for plant development and adaptation to environmental stresses, including plant defense and response to wounding.

Gene References into Functions

The involvement of UPF1, UPF2, and UPF3 in development and in response to stresses, wounding and infection by Pseudomonas syringae pv. tomato strain DC3000, were examined. PMID: 22353561
UPF1 and UPF3, which are key nonsense-mediated mRNA decay factors, may act as defense-related regulators associated with plant immunity. PMID: 22025558
AtUPF1 is involved in the control of seed size and shape and is essential for seedling growth. [AtUPF1] PMID: 16540482
lba1 is a missense mutation of UPF1 RNA helicase involved in nonsense-mediated mRNA decay PMID: 16740149
Nonsense-mediated mRNA decay and RNA interference (RNAi) in plants requires UPF1. [UPF1] PMID: 16813578
Data show that in mutants impaired in the nonsense-mediated decay (NMD) components UPF1, levels of the alternatively spliced AtGRP7 and AtGRP8 transcripts are strongly elevated, implicating UPF1 in the decay of these clock-regulated transcripts. PMID: 17924945

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Subcellular Location

Cytoplasm. Cytoplasm, P-body. Note=Remobilize from the cytoplasm into processing bodies by SMG7.

Protein Families

DNA2/NAM7 helicase family

Database Links

KEGG: ath:AT5G47010

STRING: 3702.AT5G47010.1

UniGene: At.8584

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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UPF1 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background