SEC63 Antibody

Datasheet
Code CSB-PA884652XA01SXV
Product Type Polyclonal Antibody
Uniprot No. Q9HGN7
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) SEC63 protein
Raised in Rabbit
Species Reactivity Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Translocation protein sec63 sec63 SPBC36B7.03
Immunogen Species Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Gene Names sec63
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Acts as component of the Sec62/63 complex which is involved in SRP-independent post-translational translocation across the endoplasmic reticulum (ER) and functions together with the Sec61 complex and bip1 in a channel-forming translocon complex. A cycle of assembly and disassembly of Sec62/63 complex from sec61 may govern the activity of the translocon. sec63 may affect sec61-polypeptide interactions by increasing the affinity of targeting pathways for sec61 and/or by modifying sec61 to allow more efficient polypeptide interaction. May also be involved in SRP-dependent cotranslational translocation (By similarity).
Subcellular Location Endoplasmic reticulum membrane, Multi-pass membrane protein, Nucleus membrane, Multi-pass membrane protein, Nucleus inner membrane, Multi-pass membrane protein
Database Links

KEGG: spo:SPBC36B7.03

STRING: 4896.SPBC36B7.03.1

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