UBA3 Antibody

Datasheet
Code CSB-PA909029XA01SXV
Product Type Polyclonal Antibody
Uniprot No. Q09765
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) UBA3 protein
Raised in Rabbit
Species Reactivity Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-) (Ubiquitin-activating enzyme E1 3) uba3 SPAC24H6.12c
Immunogen Species Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Gene Names uba3
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Catalytic subunit of the dimeric uba3-ula1 E1 enzyme. E1 activates NEDD8/ubl1 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-uba3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of ubc12 (By similarity).
Protein Families Ubiquitin-activating E1 family, UBA3 subfamily
Database Links

KEGG: spo:SPAC24H6.12c

STRING: 4896.SPAC24H6.12c.1

Pathway Ubiquitin mediated proteolysis

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